Glucose transporter 1, also known as GLUT1 or SLC2A1 is a protein which in humans is encoded by the SLC2A1 gene.GLUT1 facilitates the transport of glucose across the plasma membranes of mammalian cells.
GLUT1 is responsible for the low-level of basal glucose uptake required to sustain respiration in all cells. Expression levels of GLUT1 in cell membranes are increased by reduced glucose levels and decreased by increased glucose levels.
GLUT1 is also a major receptor for take-up of Vitamin C as well as glucose, especially in non vitamin C producing mammals as part of an adaptation to compensate by participating in a Vitamin C recycling process. In mammals that do produce Vitamin C, GLUT4 is often expressed instead of GLUT1.
Storage: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.