Hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor), also known as HIF1A, is a protein which in humans is encoded by the HIF1A gene.Two alternative transcripts encoding different isoforms have been identified.
The protein encoded by HIF1 is a bHLH - PAS transcription factor found in mammalian cells growing at low oxygen concentrations. It plays an essential role in cellular and systemic responses to hypoxia.This is one of the class of hypoxia inducible factors, a family that includes Hif1a, Hif2a, and Hif3a.
Storage: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.