G2/mitotic-specific cyclin-B1 is a protein that in humans is encoded by the CCNB1 gene.
Cyclin B1 is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF).
Cyclin B1 contributes to the switch-like all or none behavior of the cell in deciding to commit to mitosis
Another important function of the cyclin B1-Cdk1 complex is to break down the nuclear envelope. The nuclear envelope is a membranous structure containing large protein complexes supported by a network of nuclear lamins.
Storage: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.