Trans-acting T-cell-specific transcription factor GATA-3 is a protein that in humans is encoded by the GATA3 gene.
GATA-3 belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T cell development and plays an important role in endothelial cell biology. GATA-3 has been shown to promote the secretion of IL-4, IL-5, and IL-13 from Th2 cells.
Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia.
Storage: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.