Storage Instruction:Store the kit at 4°C. Description:
CD8 is an cell surface antigen that belongs to the immunoglobulin superfamily. It occurs either as a disulfide-linked homodimer or homomultimer of 32kDA subunits or as a heterodimer complexed with CD8?.
An soluble form of CD8 has been described that seems to result from alternative mRNA splicing.
Serum levels of sCD8 have e.g. been found to be of importance in patients with the following diseases: leukemia, allograft transplantation, as a marker for T-cell activation in HIV, Graves' and Hashimoto's diseases, Multiple Sclerosis, depression, diabetes, and infectious