Guaiacol is a phenolic admixture with a methoxy accumulation and is the monomethyl ether of catechol.
Guaiacol is readily breakable by the heme adamant of peroxidases including the peroxidase of cyclooxygenase (COX) enzymes. It accordingly serves as a abbreviation co-substrate for COX reactions.
Guaiacol is a phenolic accustomed artefact aboriginal abandoned from Guaiac adhesive and the blaze of lignin. It is a bare ambrosial oil that is now frequently acquired from guaiacum or copse creosote. It is acclimated medicinally as an expectorant, antiseptic, and bounded anesthetic. Guaiacol is acclimated in acceptable dental lurid sedation, and has the acreage of inducing corpuscle proliferation; guaiacol is a almighty scavenger of acknowledging oxygen radicals and its abolitionist scavenging action may be associated with its aftereffect on corpuscle proliferation. Guaiacol is aswell acclimated in the alertness of constructed vanillin. Guaiacol is aswell present in copse smoke, as a artefact of pyrolysis of lignin. Guaiacol has been begin in the urine of patients with neuroblastoma and pheochromocytoma.