Anti-DJ-1

Description:
DJ-1 protein has 189 amino acids and was cloned from a HeLa cell cDNA library as a novel oncogene which weakly transformed NIH3T3 cells. Transformation by DJ-1 was enhanced by
cotransfection with H-Ras or Myc. The expression of DJ-1 is induced by growth signals and it is translocated from the cytoplasm to the nucleus during the S phase, although no nuclear localization signals are present. It has been suggested that DJ-1 is a mitogen-dependent oncogene product involved in Ras-related signal transduction pathway. Northern blotting has shown that DJ-1 is ubiquitously expressed in various human tissues. 
Storage: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.