Anti-SHBG (Sex Hormone Binding Globulin)

Description:
Sex hormone-binding globulin (SHBG) is a glycoprotein that binds to sex hormones, specifically testosterone and estradiol. Other steroid hormones such as progesterone, cortisol, and other corticosteroids are bound by transcortin.
Testosterone and estradiol circulate in the bloodstream, bound mostly to SHBG and to some degree bound to serum albumin. Only a small fraction is unbound, or "free," and thus biologically active and able to enter a cell and activate its receptor. The SHBG inhibits the function of these hormones. Thus bioavailability of sex hormones is influenced by the level of SHBG. SHBG has a higher affinity for Dihydrotestosterone than for Testosterone or for Estradiol making it essential in women for regulating the bio-availability of Dihydrotestosterone.

Storage: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.