Anti-CD25/IL-2RA(Imterleukm-2 Receptor alpha)

Description:
CD25 is the alpha chain of the IL-2 receptor[1]. It is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes that associates with CD122 to form a heterodimer that can act as a high-affinity receptor for IL-2.
CD25 is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes. Its soluble form, called sIL-2R may be elevated in these diseases and is occasionally used to track disease progression.
Grauer et al. demonstrated a time-dependent accumulation of CD4+FoxP3+ Tregs in brain tumors with a syngeneic murine glioma GL261 model. They observed that the expression of CD25,

Storage: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.