Anti-CD18/LFA-1(Leukocyte Function Associated Anti-gen)

Description:
Integrin beta-2 (CD18) is a protein that in humans is encoded by the ITGB2 gene.
The ITGB2 protein product is the integrin beta chain beta 2. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.In humans lack of CD18 causes Leukocyte Adhesion Deficiency, a disease defined by a lack of leukocyte extravasation from blood into tissues.

Storage: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.