Anti-CBFA1/RUNX2 (Runt-related Transcription Factor 2)

Description:
Cbfa1/Runx2 is a key transcription factor associated with osteoblast differentiation.
This protein is a member of the RUNX family of transcription factors and has a Runt DNA-binding domain. It is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Transcript variants of the gene that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing.

Storage: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.