The Bcl-2–associated X protein, or Bax is a protein of the Bcl-2 gene family. It promotes apoptosis by competing with Bcl-2 proper.
The BAX gene was the first identified pro-apoptotic member of the Bcl-2 protein family.Bcl-2 family members share one or more of the four characteristic domains of homology entitled the Bcl-2 homology (BH) domains (named BH1, BH2, BH3 and BH4), and can form hetero- or homodimers. Bcl-2 proteins act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Orthologs of the BAX gene have been identified in most mammals for which complete genome data are available.
Storage: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.