Lp-a ELISA Kit

Storage Instruction:Store the kit at 4°C.
Description:
Lipoprotein(a) [Lp(a)] is an atherogenic lipoprotein particle formed by assembly of LDL particles and apo(a) bound to apoB-100 component of LDL . Apo(a) is the main constituent of Lp(a), has serine proteinase activity and is able of autoproteolysis . Apo(a) has 4548 amino acids, variable sizes from 200 to 700 kDa, multiple isoforms, and structural homology with plasminogen . It competes with plasminogen for its binding site, inhibiting tissue-type plasminogen activator 1 and leading to reduced fibrinolysis . The mean Lp(a) protein level ranged from 78 to 175 μg/ml depending on populations and the risk threshold is 300 μg/ml. High level of Lp(a) in blood is a risk factor for myocardial infarction (MI), coronary heart disease (CHD), cerebrovascular disease (CVD), atherosclerosis, thrombosis, and stroke .