Cathepsin ELISA Kit

Storage Instruction:Store the kit at 4°C.
Description:
The cathepsins are a group of lysosomal proteases that are active in acidic environments. As lysosomal proteases, cathepsins play an important role in protein degradation. Having broad substrate specificity, cathepsins are able to process many molecules, leading to their activation or inactivation. Approximately 11 human cathepsins (B, C, F, H, K, L, O, S, V, W and X) are cysteine proteases of the papain family, sharing similar amino acid (aa) sequences and folds . Cathepsins A and G are serine proteases and cathepsins D and E are aspartic proteases. Expression and activity of cathespins are regulated at different levels. For example, cathepsins are synthesized as inactive proenzymes and processed to become mature and active enzymes. Endogenous protein inhibitors, such as cystatins and some serpins, inhibit active cathepsin enzyme activity.