CNTF ELISA Kit

Storage Instruction:Store the kit at 4°C.
Description:
Ciliary neurotrophic factor (CNTF) is a polypeptide initially purified from 15-day chick embryo ocular tissue . Originally identified as a trophic factor for 8-day chick embryo parasympathetic neurons, CNTF has since been found to be a member of a limited family of neuropoietic cytokines that also includes Leukemia Inhibitory Factor (LIF) and Oncostatin M (OSM).  CNTF, LIF, and OSM all have similar exon organizations and a distinctive sequence in the D or C-terminal helix. For reviews on CNTF, see references 2, 4, 6 - 9. Although CNTF has no classic signal sequence, cellular secretion may employ non-classical secretion mechanisms such as ABC-transporters or novel signal recognition particle (SRP) interactions