Capsase-1 ELISA Kit

Storage Instruction:Store the kit at 4°C.
Description:
Caspase-1 (IL-1-converting enzyme, ICE) is synthesized as an inactive precursor. Dimerization and proteolysis generate an active caspase composed of two large (~20 kDa) and two small (~10 kDa) subunits. The active enzyme contains 2 active sites. An active site cysteine is located at the carboxyl terminal of each large subunit and forms a covalent bond with substrates or inhibitors. Caspase-1 cleaves substrates at the carboxyl terminal of aspartate residues.