DHEA ELISA Kit

Storage Instruction:Store the kit at 4°C.
Description:
Dehydroepiandrosterone (DHEA) is a 17-ketosteroid produced by side chain cleavage of 17-hydroxypregnenolone. DHEA is reversibly converted to its sulfate ester (DHEA-S) and Androstendiol. The human adrenal glands secrete both DHEA and DHEA-S which in turn serve as the precursors for both estrogenic and androgenic steroids3. DHEA weakly binds to corticosteroid binding globulin and albumin and strongly binds to sex hormone binding globulin4. DHEA is excreted in urine in its sulfate form, conjugated to glucorinide or in its free form. DHEA levels peak in early childhood and decline with age5. DHEA has been linked to a number of physiological conditions including depression, systemic lupus erythematosus and rheumatoid arthritis.