FGF-acidic ELISA Kit

Storage Instruction:Store the kit at 4°C.
Description:
Fibroblast Growth Factor acidic (FGF acidic), also known as FGF-1, endothelial cell growth factor (ECGF), and heparin-binding growth factor-1 (HBGF-1), is a 17 - 18 kDa non-glycosylated polypeptide that is secreted by a variety of cell types . The molecule is synthesized as a 155 amino acid (aa) protein that has no distinctive signal peptide sequence. As such, this precludes its secretion via classical ER/Golgi pathways. It appears, however, that there is a unique secretory pathway that involves heat shock proteins, phosphatidyl serine, synaptotagmin-1 and annexin . The outcome of FGF acidic secretion is an extracellular disulfide-linked homodimer whose covalent bonds can be broken by reducing agents to release potentially bioactive FGF acidic.