IL-11 ELISA Kit

Storage Instruction:Store the kit at 4°C.
Description:
Interleukin-11, also known as adipogenesis inhibitory factor (AGIF) and oprelvekin, is a member of the GP130 family of cytokines. These cytokines drive the assembly of multi-subunit receptor complexes containing at least one GP130. IL-11 exerts biological activity through IL-11 receptor by utilizing the gp130 molecule as the signaling component of its receptor. Interleukin 11 (IL-11) is a highly conserved precursor protein of 19kDa with 199 amino acids. IL-11 is thermally stable and contains no cysteine residues. Many cell and tissue types throughout the body, such as CNS, thymus, lung, bone, connective tissues, uterus, skin, and testis, can produce IL-11 depending on the local environment of the cell or tissue. IL11 promotes primary and secondary immune responses in vitro and in vivo and modulates antigen-specific antibody reactions. IL-11 has activity in bone metabolism and activity in protection and restoration of the gastrointestinal mucosa. Human endometrial stromal cells produce biologically active IL-11, which promotes progesterone-induced decidualization.